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MCAT Practice · Reasoning about the Design & Execution of Research

MCAT Question: Researchers are interested in investigating the effects of a new…

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Researchers are interested in investigating the effects of a new drug (Drug X) on pain perception in patients with chronic back pain. They design a randomized, double-blind, placebo-controlled clinical trial. In this study, participants are randomly assigned to one of three groups: Group 1: Receives Drug X (treatment group). Group 2: Receives a placebo (control group 1). Group 3: Receives no intervention (control group 2). Pain levels are measured using a standardized scale before and after the intervention period. Which of the following best describes a limitation of this study design?

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